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KMID : 1144520210330010039
Knee Surgery & Related Research
2021 Volume.33 No. 1 p.39 ~ p.39
Botulinum toxin injections as salvage therapy is beneficial for management of patellofemoral pain syndrome
Kesary Yuval

Singh Vivek
Frenkel-Rutenberg Tal
Greenberg Arie
Dekel Shmuel
Schwarzkopf Ran
Snir Nimrod
Abstract
Purpose: Patellofemoral pain syndrome (PFPS) is a common pathology usually presenting with anterior or retropatellar pain. It is associated with a relative imbalance between the vastus medialis oblique (VMO) and the vastus lateralis (VL) muscles. This can lead to considerable morbidity and reduced quality of life (QOL). This study aims to assess the long-term functional outcome of PFPS treated with VL muscle botulinum toxin A (BoNT-A) injection.

Materials and methods: A retrospective review was performed on 26 consecutive patients (31 knees) with a mean age of 50.1 years (¡¾?19.7 years) who were treated with BoNT-A injections to the VL muscle followed by physiotherapy between 2008 and 2015. Pre- and post-treatment pain levels (numerical rating scale, NRS), QOL (SF-6D), and functional scores (Kujala and Lysholm questionnaires) were measured. Demographics, physical therapy compliance, previous surgeries, perioperative complications, and patient satisfaction levels were collected.

Results: The mean follow-up time was 58.8?¡¾?36.4 months. There were significant improvements in all the examined domains. The average pain score (NRS) decreased from 7.6 to 3.2 (P?
Conclusions: A single intervention of BoNT-A injections to the VL muscle combined with physiotherapy is beneficial for the treatment of patients with persistent PFPS.
KEYWORD
Patella, Knee, Patellofemoral pain, Physical therapy, Botulinum toxin, Muscle imbalance
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